Catlytic type: Cysteine; All the peptidases of family C14 have a strict requirement for the amino acid in P1 to be aspartate, however  the substrate specificities of the individual caspases are distinct and determined by the residues present in the pockets of P2, P3 and P4.; caspases that have strict specificity for the hydrolysis of aspartyl bonds
Cytosolic endopeptidases termed caspases that have strict specificity for the hydrolysis of aspartyl bonds